Jul 07, 2024Potent, Specific, and Durable Liver Editing of PCSK9 in Preclinical Studies of the CRISPR Base Editing Medicine VERVE-101 VERVE-101 2024 PCSK9
May 28, 2024An investigational in vivo base editing medicine targeting ANGPTL3, VERVE-201, achieves precise, and durable liver editing in nonclinical studies EAS VERVE-201 2024 ANGPTL3
May 17, 2024Proof-of-concept for in vivo Base Editing to Inactivate the PCSK9 Gene and Lower LDL-Cholesterol in Humans TIDES VERVE-101, VERVE-102, VERVE-201 2024 ANGPTL3, LPA, PCSK9
May 11, 2024Characterization of Guide RNA Site Consistency Across Ancestries and the Potential for Off-Target Editing with the Clinical-Stage Base Editing Medicine, VERVE-101 ASGCT VERVE-101 2024 PCSK9
Nov 13, 2023Interim Results from the heart-1 Trial of VERVE-101 & Verve Corporate Updates AHA VERVE-101, VERVE-102, VERVE-201 2023 ANGPTL3, PCSK9
Aug 28, 2023An investigational in vivo base editing medicine targeting ANGPTL3, VERVE-201, achieves potent and LDLR-independent liver editing in mouse models ESC VERVE-201 2023 ANGPTL3
May 26, 2023Developing ‘once-and-done’ gene editing medicines to treat cardiovascular disease EAS VERVE-101, VERVE-201, GalNAc-LNP 2023 ANGPTL3, PCSK9