Verve Therapeutics is a biotechnology company created with a singular focus: to protect the world from heart disease. The company brings together human genetics analysis and gene editing — two of the biggest breakthroughs in 21st century biomedicine — to develop transformative therapies for coronary heart disease. Verve is developing medicines, administered once in life, to safely edit the genome of adults to permanently lower LDL cholesterol and triglyceride levels and thereby treat coronary heart disease. Founded by world-leading experts in cardiovascular medicine, human genetics and gene editing, Verve is backed by a top-tier syndicate of investors, including GV (formerly Google Ventures), ARCH Venture Partners, F-Prime Capital, Biomatics Capital, Wellington Management, Casdin Capital, and Partners Innovation Fund. Verve is headquartered in Cambridge, Massachusetts.
Verve is seeking a Senior Scientist, Analytical Chemistry to support analytical method development and testing of oligonucleotide drug substance and drug product across all stages of development. The role is flexible with respect to level of experience and title. This individual will be involved across development stages in developing analytical and bioanalytical methods for mRNA and guide RNA and characterization. The successful candidate will be responsible for designing and executing analytical methods from lab scale to preclinical development, interpreting data; analytical methods transfer to CMOs and oversight thereof. The scientist in this position will be part of an integrated R&D project team that aims to advance preclinical gene editing candidates into the clinic. This is a hands-on role with a great degree of independence. Candidates should have proven experience in oligonucleotide analytical HPLC and LC-MS method development, quality control processes and hand-on experience with state-of-the-art analytical instruments. Knowledge/hands-on experience in oligonucleotide synthesis methods, purification and process development are a plus. Candidates should have earned a degree in chemistry, analytical chemistry, biochemistry, pharmacy or related area and should have multiple years of experience in a biotech laboratory setting.
Verve Therapeutics is proud to be an equal opportunity workplace and is an affirmative action employer. We are committed to equal employment opportunity regardless of race, color, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, gender identity or Veteran status. If you have a disability or special need that requires accommodation, please let us know.
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