Verve Therapeutics is a biotechnology company created with a singular focus to protect the world from heart disease. Verve is committed to discovering and developing therapies that safely edit the genome of adults to confer lifelong protection from coronary artery disease, the most common form of heart disease and the leading cause of death worldwide. Headquartered in Cambridge, Massachusetts, Verve was founded by world-leading experts in cardiovascular medicine and gene editing and is backed by a top-tier syndicate of investors, including GV (formerly Google Ventures), ARCH Venture Partners, F-Prime Capital Partners, and Biomatics Capital.
Verve is seeking a Senior/Principal Scientist to lead the in vivo pharmacology efforts characterizing Crispr/Cas9-mediated gene editing in preclinical species. You will develop the strategy and oversee in vivo studies with lipid nanoparticles (LNPs) that target the liver. The role requires in depth knowledge of animal models and in vitro assays to characterize PK/PD, efficacy and toxicology of drug candidates in Verve’s pipeline of cardiovascular targets. This position is an integral part of a multidisciplinary team within the company but will also work closely with collaborators at numerous CROs. Candidates with a degree in biology, biochemistry, chemistry or pharmaceutical science should possess a successful track record of advancing drug candidates towards the clinic gathered over 10-15 years (M.Sc.) or 5-8 years (Ph.D.) of working in pharmaceutical laboratories.
Verve Therapeutics is proud to be an equal opportunity workplace and is an affirmative action employer. We are committed to equal employment opportunity regardless of race, color, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, gender identity or Veteran status. If you have a disability or special need that requires accommodation, please let us know.
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